|This is your (my) guild bank on the shuffle (click image to enlarge).|
Shuffling is a really great combination of professions, arguably the most lucrative combination of professions in game throughout expansions. There of course is one caveat to shuffling though, that it's very time consuming. Now there are ways that you can cut down on the amount of time you spend mashing buttons using tools from The Consortium, but you still need to have that time available to be in game and not doing something else in game. If you don't have that kind of time, odds are that other professions might suit you better. A lot of professions with daily CDs can really add a lot of value to items in little time. Professions like Tailoring, Leatherworking, and Blacksmithing (etc.) might suit you better if you don't have a lot of in game time, and want to get the most bang for your buck. In 5 minutes switching between multiple toons doing daily CDs, you could make as much as you could shuffling for say 30 minutes. This of course is a ballpark estimate, but you get the point.
If you're someone who enjoys playing the game for raiding, PvP, or whatever it is you may enjoy that's not gold making, and just want to make some coin "part time", shuffling is most likely not for you. It takes a lot of time investment, and not just in the actual processing of the mats.
The shuffle can make you a ton of gold, and the more time you put into it, the more gold you'll make. This is best summarized by a recent thread on the Consortium Forum, where a user asked "How much do you make on the shuffle daily?" to which Kathroman replied "As much as I want to." More in depth discussion occurred that you can check out, but that's the bottom line. The main point though is that there is always profit potential in this market, hindered only by the amount of time that you have to dedicate to it and number of times per day you can post. Shuffling will nearly always make you gold, but quite like all other professions there's a breaking point where it'd be more efficient to just go out and farm, or you start hurting your own profits by over saturating the market. Basically, know your limits here. If this is not something you'll keep up with, getting into it may just be a waste of time for you.
The last thing I will say about Shuffling (in this post at least) is to keep an eye on your rare gem ceiling, the highest price you will possibly pay for 1 rare gem. I calculate this by using GIO numbers: 1 rare gem, 6 uncommon gems, .5 Serpent's Eye per stack. Ignoring Serpent's Eye's (although you could factor them in if you really wanted to), and assuming I go the route of guaranteed income with the 6 uncommon gems, making jewelry and vendoring it (again, not necessarily best route, but the minimum I can be guaranteed to make), the net profit on those is about 16g. I pay 50g/stack for GIO, so the ceiling for my rare gems is:
50g - 16g = 34g/gem.
That's the theoretical most I will pay ever for a rare gem at that stack price. Then I can look at my profits and make sure I'm making smart choices. Some quick math can save you headaches in the long run. Again this is the MAXIMUM price I'll ever pay for a gem at these stack prices.
Shuffling is by far one of the most profitable profession combos in game when utilized properly. When I wrote my post for Nev's 20 Days of Goldmaking that had the prompt "Which Market has made you the most through the years?" I wrote my response on Jewelcrafting. Obviously I (and many other serious gold makers) see this as a great method of making profits in WoW, but it's not right for everyone. If you have the time though, the profitabilies are endless!
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